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最終更新日：2024/01/31
安藤 啓
アンドウ アキラ
(Akira Ando)
論文
- タイトル
- タイトル（英）
- Effects of Capsinoid Intake on Brown Adipose Tissue Vascular Density and Resting Energy Expenditure in Healthy, Middle-Aged Adults: A Randomized, Double-Blind, Placebo-Controlled Study.
- 参照URL
- https://researchmap.jp/akira_ando/published_papers/31765768
- 著者
- 著者（英）
- Sayuri Fuse,Tasuki Endo,Riki Tanaka,Miyuki Kuroiwa,Akira Ando,Ayami Kume,Akiko Yamamoto,Kanna Kuribayashi,Shinji Somekawa,Masamichi Takeshita,Masaki Hashimoto,Ryotaro Kime,Yuko Kurosawa,Takafumi Hamaoka
- 担当区分
- 概要
- 概要（英）
- Capsinoids are some of the most promising ingredients to increase energy expenditure (EE) due to brown adipose tissue (BAT) activation. However, there is limited information regarding the effect of prolonged capsinoid ingestion (CI) on BAT activity and resting EE (REE) in healthy, middle-aged, normal to overweight subjects (Subhealthy) with distinct BAT characteristics. We examined the changes in BAT density (BAT-d), using near-infrared time-resolved spectroscopy, and REE/kg induced by daily CI. Forty Subhealthy [age, 43.8 (mean) years; BMI, 25.4 kg/m2] received either capsinoid (9 mg/day) or a placebo daily for 6 weeks in a double-blind design. Total hemoglobin concentration in the supraclavicular region ([total-Hb]sup), an indicator of BAT-d, and REE/kg were measured. The changes in post-intervention [total-Hb]sup were greater in the capsinoid group (CA-G) than in the placebo group (PL-G) [5.8 µM (+12.4%) versus 1.0 µM (+2.1%); p = 0.017]. There was a significant relationship between BAT-d and REE/kg; however, post-supplementation REE/kg was not significantly different between the two groups (p = 0.228). In the overweight subgroup, changes in REE/kg were greater in the CA-G than in the PL-G [0.6 cal/kg/min (+4.3%) versus -0.3 cal/kg/min (-2.1%); p = 0.021]. CI enhanced [total-Hb]sup, a reflection of BAT-d, showing a good correlation with REE in Subhealthy.
- 出版者・発行元
- 出版者・発行元（英）
- 誌名
- 誌名（英）
- Nutrients
- 巻
- 12
- 号
- 9
- 開始ページ
- 2676
- 終了ページ
- 出版年月
- 2020年9月2日
- 査読の有無
- 査読有り
- 招待の有無
- 掲載種別
- 研究論文（学術雑誌）
- ISSN
- DOI URL
- https://doi.org/10.3390/nu12092676
- 共同研究・競争的資金等の研究課題