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最終更新日：2024/07/17
赤澤 暢彦
(Nobuhiko Akazawa)
論文
- タイトル
- タイトル（英）
- Combined effects of sleep and objectively-measured daily physical activity on arterial stiffness in middle-aged and older adults.
- 参照URL
- https://researchmap.jp/nobakazawa/published_papers/46587288
- 著者
- 著者（英）
- Youngju Choi,Keisei Kosaki,Nobuhiko Akazawa,Koichiro Tanahashi,Seiji Maeda
- 担当区分
- 概要
- 概要（英）
- Although sleep quality and physical activity (PA) may influence on arterial stiffness, the combined effects of these two factors on arterial stiffness remain unknown. A total of 103 healthy middle-aged and older men and women (aged 50-83 years) with no history of cardiovascular disease and depression were included in this study. Arterial stiffness was measured using carotid-femoral pulse wave velocity (cfPWV), brachial-ankle PWV (baPWV), and femoral-ankle PWV (faPWV). Poor sleepers were defined as those with a Pittsburgh Sleep Quality Index score of >5.5. Using an accelerometer for seven consecutive days, low levels of PA were defined as low moderate-to-vigorous-intensity PA (MVPA) <19.0 min/day and low step counts <7100 steps/day, respectively. Poor sleepers with low PA levels, as determined by MVPA and daily steps, showed higher cfPWV, but not faPWV or baPWV, in middle-aged and older adults. Furthermore, in the analysis of covariance (ANCOVA) analyses adjusted for age, obesity, dyslipidemia, and sedentary behavior, the cfPWV result remained significant. Our study revealed that the coexistence of poor sleep quality and decreased PA (low MVPA or daily steps) might increase central arterial stiffness in middle-aged and older adults. Therefore, adequate sleep (good and sufficient sleep quality) and regular PA, especially at appropriate levels of MVPA (i.e., at least of 7100 steps/day), should be encouraged to decrease central arterial stiffness in middle-aged and older adults.
- 出版者・発行元
- 出版者・発行元（英）
- 誌名
- 誌名（英）
- Experimental gerontology
- 巻
- 188
- 号
- 開始ページ
- 112397
- 終了ページ
- 112397
- 出版年月
- 2024年4月
- 査読の有無
- 招待の有無
- 掲載種別
- 研究論文（学術雑誌）
- ISSN
- DOI URL
- https://doi.org/10.1016/j.exger.2024.112397
- 共同研究・競争的資金等の研究課題