News
人材検索について
ハイパフォーマンススポーツに係る研究者やサポートスタッフ等の人材情報の検索ができます。HPSCに現在勤務する職員（HPSCスタッフ）、HPSCの勤務経験者（HPSC OB/OG）、HPSCの各種事業における協力者（HPSC事業協力者）のカテゴリーに分けております。人材データベースへのご登録はHPSCからご依頼させて頂いた方のみとしております。
最終更新日：2025/02/21
谷村 祐子
タニムラ ユウコ
(Yuko Tanimura)
論文
- タイトル
- タイトル（英）
- Responses of complement C1q/tumor necrosis factor-related proteins to acute aerobic exercise
- 参照URL
- https://researchmap.jp/tanimurayuko/published_papers/40479333
- 著者
- 著者（英）
- Michihiro Kon,Yuko Tanimura
- 担当区分
- 概要
- 概要（英）
- Aerobic exercise is an effective therapeutic strategy to manage metabolic disorders. However, the mechanisms of aerobic exercise-induced improvements in metabolic diseases are not completely understood. Complement C1q/tumor necrosis factor-related protein (CTRP) 1, CTRP3, CTRP5, and CTRP9 have important roles in improving metabolic disorders via the adenosine monophosphate-activated protein kinase signaling pathway. In this study, we investigated the effects of acute aerobic exercise on circulating CTRP1, CTRP3, CTRP5, and CTRP9 levels in human participants. Eight healthy males with an age of 20.4 ± 0.2 years, height 173.1 ± 1.7 cm, body mass 68.0 ± 1.8 kg, body mass index 22.7 ± 0.7 kg/m2, and maximal oxygen uptake (VO2max) 51.3 ± 2.5 mL/kg/min performed acute aerobic cycling exercise at 75 % of their VO2max for 30 min (data are mean ± standard error). Blood samples were obtained before; immediately after; and 30, 60, and 120 min after exercising. Serum concentrations of CTRP1, CTRP3, CTRP5, CTRP9, tumor necrosis factor-α (TNF-α), and insulin were measured. The CTRP1 concentration significantly increased immediately after exercising and remained elevated for up to 120 min (p < 0.01). The CTRP3 concentration significantly increased at 60 min after exercise (p < 0.05), and the increasing trend continued until at least 120 min after exercise (p < 0.01). The CTRP5, CTRP9, TNF-α, and insulin concentrations significantly increased immediately after exercise (p < 0.05, p < 0.01, p < 0.05, and p < 0.05, respectively) and decreased thereafter. A significant correlation was observed between the peak post-exercise concentrations of CTRP1 and TNF-α (p < 0.05); however, no correlation was observed between the peak post-exercise concentrations of CTRP3 and insulin. The results of this study indicate that acute aerobic exercise may enhance the secretion of CTRP1, CTRP3, CTRP5, and CTRP9 in healthy adults.
- 出版者・発行元
- 出版者・発行元（英）
- Elsevier BV
- 誌名
- 誌名（英）
- Cytokine
- 巻
- 161
- 号
- 開始ページ
- 156083
- 終了ページ
- 156083
- 出版年月
- 2022年11月
- 査読の有無
- 査読有り
- 招待の有無
- 掲載種別
- 研究論文（学術雑誌）
- ISSN
- 1043-4666
- DOI URL
- https://doi.org/10.1016/j.cyto.2022.156083
- 共同研究・競争的資金等の研究課題