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最終更新日:2026/06/18

近藤 衣美

コンドウ エミ (Emi Kondo)
論文
タイトル
タイトル(英)
Comparison of different bromide equilibrium times to measure extracellular water in athletes: analysis before and after a 4-day intervention to increase water intake.
参照URL
https://researchmap.jp/E_Kondo/published_papers/54178280
著者
著者(英)
Filipe Jesus,Rúben Francisco,Emi Kondo,Catarina L Nunes,Luís B Sardinha,Hiroyuki Sagayama,Dale A Schoeller,Analiza M Silva
担当区分
概要
概要(英)
BACKGROUND: Bromide (Br-) dilution is the criterion to determine extracellular water. While 3h equilibrium is typically used in athletes, the optimal equilibrium time has not been assessed. The study aimed to determine the optimal time of equilibrium of Br- in athletes before and after increasing water intake (WI). METHODS: Thirty-one athletes [21.5 (0.8) years; 41.9% females] from the H2OAthletes randomized controlled trial (clinicaltrials.gov ID: NCT05380089) were included in this longitudinal sub-analysis. Athletes were assessed before and after a 4-day intervention to increase WI (experimental group) or maintain WI (control group). Br- dilution was assessed through saliva before and 3, 4, and 5h post-dose. Total body water (TBW) and water turnover (rH2O) was measured through deuterium dilution. Body composition was determined through the 4-compartment model. RESULTS: At baseline, most athletes achieved equilibrium at 3h (45.2%) or 4h (48.4%). After the intervention, most athletes (70.4%) achieved peak concentration at 3h, with fewer reaching at 4h (14.8%) or 5h (14.8%). No differences in body composition, TBW, or rH2O were observed between athletes grouped according to the time of peak, both before and after the intervention. Time of peak was not associated with the intervention group [x2 (1)=1.439; p=0.487] or sex both before [x2 (1)=0.230; p=0.891] and after the intervention [x2 (1)=0.728; p=0.695]. CONCLUSION: Br- equilibrium appears to occur 3h to 4h post-dosing, suggesting it is unnecessary to extend the collection to 5h, reducing the burden on athletes. Future studies should include larger samples to confirm the current findings.
出版者・発行元
出版者・発行元(英)
誌名
誌名(英)
Clinical nutrition ESPEN
開始ページ
103398
終了ページ
103398
出版年月
2026年6月12日
査読の有無
招待の有無
掲載種別
研究論文(学術雑誌)
ISSN
DOI URL
https://doi.org/10.1016/j.clnesp.2026.103398
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