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最終更新日：2026/03/17
下山 寛之
サガヤマ ヒロユキ
(Hiroyuki Sagayama)
論文
- タイトル
- Sex Differences in Measures of Energy Expenditure and Body Composition in Young, Middle-Aged, and Older Adults
- タイトル（英）
- Sex Differences in Measures of Energy Expenditure and Body Composition in Young, Middle-Aged, and Older Adults
- 参照URL
- https://researchmap.jp/gs070100/published_papers/52111821
- 著者
- Cabre, Hannah E.,Marlatt, Kara L.,Fernández-Verdejo, Rodrigo,Beyl, Robbie,Redman, Leanne M.,Ainslie, Philip N.,Alemán-Mateo, Heliodoro,Andersen, Lene F.,Anderson, Liam J.,Arab, Lenore,Bedu-Addo, Kweku,Bonomi, Alberto G.,Bouten, Carlijn Vc,Bovet, Pascal,Brage, Soren,Buchowski,Maciej S.,Butte, Nancy F.,Camps, Stefan G.,Casper, Regina,Close, Graeme L.,Colbert, Lisa H.,Cooper, Jamie A.,Cooper, Richard,Das, Sai Krupa,Deb, Sanjoy,Forrester, Terrence,Gillingham, Melanie,Goris, Annelies H.,Gurven, Michael,Hambly, Catherine,Hu, Sumei,Joosen,Annemiek M.,Katzmarzyk, Peter,Kempen, Kitty P.,Kimura, Misaka,Kraus, William E.,Kriengsinyos, Wantanee,Kushner, Robert F.,Lessan, Nader,Löf, Marie,Martin, Corby K.,Matsiko, Eric,Medin, Anine C.,Morehen, James C.,Morton, James P.,Neuhouser, Marian L.,Prentice, Ross L.,Racette, Susan B.,Raichlen, David A.,Reynolds, Rebecca M.,Roberts, Susan B.,Sardinha, Luís B.,Schuit, Albertine J.,Silva, Analiza M.,Urlacher, Samuel S.,Valencia,Mauro Eduardo,Van Etten, Ludo M.,Verbunt, Jeanine A.,Wilson, George,Wood,Brian M.,Yoshida, Tsukasa,Zhang, Xueying,Murphy-Alford, Alexia J.,Loechl, Cornelia U.,Luke, Amy H.,Pontzer, Herman,Rood, Jennifer,Sagayama, Hiroyuki,Schoeller, Dale A.,Westerterp, Klaas R.,Wong, William W.,Yamada, Yosuke,Speakman, John R.,Ravussin, Eric
- 著者（英）
- Cabre, Hannah E.,Marlatt, Kara L.,Fernández-Verdejo, Rodrigo,Beyl, Robbie,Redman, Leanne M.,Ainslie, Philip N.,Alemán-Mateo, Heliodoro,Andersen, Lene F.,Anderson, Liam J.,Arab, Lenore,Bedu-Addo, Kweku,Bonomi, Alberto G.,Bouten, Carlijn Vc,Bovet, Pascal,Brage, Soren,Buchowski,Maciej S.,Butte, Nancy F.,Camps, Stefan G.,Casper, Regina,Close, Graeme L.,Colbert, Lisa H.,Cooper, Jamie A.,Cooper, Richard,Das, Sai Krupa,Deb, Sanjoy,Forrester, Terrence,Gillingham, Melanie,Goris, Annelies H.,Gurven, Michael,Hambly, Catherine,Hu, Sumei,Joosen,Annemiek M.,Katzmarzyk, Peter,Kempen, Kitty P.,Kimura, Misaka,Kraus, William E.,Kriengsinyos, Wantanee,Kushner, Robert F.,Lessan, Nader,Löf, Marie,Martin, Corby K.,Matsiko, Eric,Medin, Anine C.,Morehen, James C.,Morton, James P.,Neuhouser, Marian L.,Prentice, Ross L.,Racette, Susan B.,Raichlen, David A.,Reynolds, Rebecca M.,Roberts, Susan B.,Sardinha, Luís B.,Schuit, Albertine J.,Silva, Analiza M.,Urlacher, Samuel S.,Valencia,Mauro Eduardo,Van Etten, Ludo M.,Verbunt, Jeanine A.,Wilson, George,Wood,Brian M.,Yoshida, Tsukasa,Zhang, Xueying,Murphy-Alford, Alexia J.,Loechl, Cornelia U.,Luke, Amy H.,Pontzer, Herman,Rood, Jennifer,Sagayama, Hiroyuki,Schoeller, Dale A.,Westerterp, Klaas R.,Wong, William W.,Yamada, Yosuke,Speakman, John R.,Ravussin, Eric
- 担当区分
- 概要
- [BACKGROUND] Total daily energy expenditure (TDEE) is vital for energy balance and cardiometabolic health, yet its trajectory across the lifespan, particularly in females, remains poorly understood. [OBJECTIVES] We sought to examine the effects of aging and sex on body composition and TDEE. [METHODS] In a cross-sectional analysis of data from research centers across 9 European Countries and the United States from the International Atomic Energy Agency database, TDEE and body composition measures of 2326 participants (1560W/766M; 50.7 ± 12 .6 y) were stratified across age groups: young (30-39 y; YOUNG), middle-aged (40-54 y; MID), and old (55-70 y; OLD). Doubly labeled water was used to estimate TDEE and fat-free mass (FFM). Fat mass (FM) was calculated as the difference between body mass and FFM, and %fat was ratio between FM and body mass as a percentage. Linear models were used for analysis. [RESULTS] Females demonstrated greater FM and lower FFM with each age group, compared with males (P < 0.001). In females, OLD had lower absolute TDEE than YOUNG (-217 kcal/d, P < 0.001) and MID (-208 kcal/d, P < 0.001). Male absolute TDEE was lowered across all age groups (OLD compared with YOUNG: -334 kcal/d; OLD compared with MID: -210 kcal/d; MID compared with YOUNG: -124 kcal/d; P < 0.001). Adjusted TDEE was similar within age groups between females and males. [CONCLUSIONS] These results suggest that age influences changes in body composition and energy expenditure similarly between males and females. The most significant change in TDEE occurs as individuals transition from middle age to older adulthood. Females generally have a higher percentage of %fat and FM, along with lower FFM, compared with males across all age groups. These findings are important for understanding how aging affects metabolism and body composition, which could inform sex-specific health strategies and interventions.
- 概要（英）
- [BACKGROUND] Total daily energy expenditure (TDEE) is vital for energy balance and cardiometabolic health, yet its trajectory across the lifespan, particularly in females, remains poorly understood. [OBJECTIVES] We sought to examine the effects of aging and sex on body composition and TDEE. [METHODS] In a cross-sectional analysis of data from research centers across 9 European Countries and the United States from the International Atomic Energy Agency database, TDEE and body composition measures of 2326 participants (1560W/766M; 50.7 ± 12 .6 y) were stratified across age groups: young (30-39 y; YOUNG), middle-aged (40-54 y; MID), and old (55-70 y; OLD). Doubly labeled water was used to estimate TDEE and fat-free mass (FFM). Fat mass (FM) was calculated as the difference between body mass and FFM, and %fat was ratio between FM and body mass as a percentage. Linear models were used for analysis. [RESULTS] Females demonstrated greater FM and lower FFM with each age group, compared with males (P < 0.001). In females, OLD had lower absolute TDEE than YOUNG (-217 kcal/d, P < 0.001) and MID (-208 kcal/d, P < 0.001). Male absolute TDEE was lowered across all age groups (OLD compared with YOUNG: -334 kcal/d; OLD compared with MID: -210 kcal/d; MID compared with YOUNG: -124 kcal/d; P < 0.001). Adjusted TDEE was similar within age groups between females and males. [CONCLUSIONS] These results suggest that age influences changes in body composition and energy expenditure similarly between males and females. The most significant change in TDEE occurs as individuals transition from middle age to older adulthood. Females generally have a higher percentage of %fat and FM, along with lower FFM, compared with males across all age groups. These findings are important for understanding how aging affects metabolism and body composition, which could inform sex-specific health strategies and interventions.
- 出版者・発行元
- 出版者・発行元（英）
- 誌名
- Current developments in nutrition
- 誌名（英）
- Current developments in nutrition
- 巻
- 10
- 号
- 1
- 開始ページ
- 終了ページ
- 出版年月
- 2026年1月
- 査読の有無
- 査読有り
- 招待の有無
- 掲載種別
- 研究論文（学術雑誌）
- ISSN
- 2475-2991
- DOI URL
- https://doi.org/10.1016/j.cdnut.2025.107614
- 共同研究・競争的資金等の研究課題