人材検索について
ハイパフォーマンススポーツに係る研究者やサポートスタッフ等の人材情報の検索ができます。HPSCに現在勤務する職員（HPSCスタッフ）、HPSCの勤務経験者（HPSC OB/OG）、HPSCの各種事業における協力者（HPSC事業協力者）のカテゴリーに分けております。人材データベースへのご登録はHPSCからご依頼させて頂いた方のみとしております。
最終更新日：2026/02/04
竹村 藍
タケムラ アイ
(Ai Takemura)
論文
- タイトル
- タイトル（英）
- Mild hyperbaric oxygen enhances recovery of the plantaris muscle atrophy induced by cast immobilization of the hindlimb in male rats
- 参照URL
- https://researchmap.jp/Atakemura/published_papers/52147719
- 著者
- 著者（英）
- Ai Takemura,Tatsuro Egawa,Ryo Takagi,Ryota Iyama,Zhao Haiyu,Shinichiro Suzuki,Reika Fujino,Takuya Fukunaga,Tatsuya Hayashi,Satoshi Fujita
- 担当区分
- 筆頭著者
- 概要
- 概要（英）
- Abstract Loss of muscle mass is associated with muscle functional decline and mortality. The present study aimed to determine whether exposure to mild hyperbaric oxygen (MHO) during and after casting immobilization reduces muscle atrophy. We distributed eight‐week‐old rats into control (CON), cast immobilization (Cast), and Cast + MHO (1.3 atmosphere absolute with 38% oxygen) groups. Rats were cast for 2 weeks under the normal or MHO condition, followed by a two‐week recovery period under the same condition after cast removal. The plantaris muscle weight (mg/g BW) decreased by approximately 11.5% in the Cast group compared to the CON group (p < 0.01), while there were no differences between the CON and Cast + MHO groups, suggesting that MHO enhanced the recovery of muscle atrophy. However, the soleus muscle weight (mg/g BW) decreased by casting immobilization, regardless of MHO. The enzyme activity by succinate dehydrogenase (SDH) staining in the plantaris muscle was lower in the Cast group than in the CON group (p < 0.01), while there were no differences between the CON and Cast + MHO groups. In summary, MHO enhances the recovery of plantaris muscle atrophy and partially attenuates the decreased SDH activity after cast immobilization of hindlimb in rats.
- 出版者・発行元
- 出版者・発行元（英）
- Wiley
- 誌名
- 誌名（英）
- Physiological Reports
- 巻
- 13
- 号
- 9
- 開始ページ
- 終了ページ
- 出版年月
- 2025年5月5日
- 査読の有無
- 招待の有無
- 掲載種別
- 研究論文（学術雑誌）
- ISSN
- 2051-817X
- DOI URL
- https://doi.org/10.14814/phy2.70350
- 共同研究・競争的資金等の研究課題