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最終更新日:2025/11/28
近藤 衣美
コンドウ エミ
(Emi Kondo)
論文
- タイトル
- タイトル(英)
- Association of SARC-F with muscle mass, strength, and quality derived from bioelectrical impedance spectroscopy for sarcopenia assessment.
- 参照URL
- https://researchmap.jp/E_Kondo/published_papers/51754341
- 著者
- 著者(英)
- Tsukasa Yoshida,Yuki Nishida,Emi Kondo,Miwa Yamaguchi,Aya Itoi,Hiroyuki Shirato,Hirohiko Hirano,Satoshi Sasaki,Minoru Yamada,Shigeho Tanaka,Misaka Kimura,Fuminori Katsukawa,Yosuke Yamada
- 担当区分
- 概要
- 概要(英)
- The SARC-F is a 5-item questionnaire screening for patients at risk of sarcopenia. The electrical properties of tissues derived from bioelectrical impedance spectroscopy (BIS), including phase angle (PhA) and intracellular-extracellular water ratio (ICW/ECW) indices, are biomarkers of age-related loss of skeletal muscle quantity and quality. The purpose of the current study was to examine the association between SARC-F and muscle mass, strength, muscle-specific strength, and muscle quality as assessed by BIS and hand grip strength (HGS). Sarcopenia risk was assessed using the SARC-F questionnaire. BIS was used to obtain skeletal muscle mass (SMM) and skeletal muscle mass index (SMI), PhA, ICW/ECW index, membrane capacitance (Cm) and characteristic frequency (fc) for assessing muscle quantity and quality. HGS was evaluated, and muscle-specific strength (HGS/SMM) was calculated. The Pearson correlation coefficient was used to examine the associations between SARC-F scores and each muscle parameter. A total of 205 older adults aged 65-99 years were included in the current cross-sectional analysis. Of those, 142 were community-dwelling healthy older adults (110 women and32 men) and 63 were the older adults living in special nursing homes for the older adults (45 women and 18 men). SARC-F was significantly correlated with SMM, SMI, HGS, and HGS/SMM in both men and women (p < 0.05). SARC-F was also correlated with PhA, ICW/ECW index, Cm, and fc in both men and women (p < 0.001). The SARC-F score was associated with SMM, HGS, HGS/SMM, PhA, ICW/ECW index, Cm, and fc independently of age, sex, height, and BMI. SARC-F is a subjective yet simple assessment tool for muscle mass, strength, and quality relevant to sarcopenia.
- 出版者・発行元
- 出版者・発行元(英)
- 誌名
- 誌名(英)
- Scientific reports
- 巻
- 15
- 号
- 1
- 開始ページ
- 41905
- 終了ページ
- 41905
- 出版年月
- 2025年11月25日
- 査読の有無
- 査読有り
- 招待の有無
- 掲載種別
- 研究論文(学術雑誌)
- ISSN
- DOI URL
- https://doi.org/10.1038/s41598-025-25862-z
- 共同研究・競争的資金等の研究課題