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最終更新日：2024/06/14
今井 菜美
イマイ ナミ
(Nami Imai)
論文
- タイトル
- タイトル（英）
- Association between trunk-to-peripheral fat ratio and renal function in elderly Japanese men: baseline data from the Fujiwara-kyo Osteoporosis Risk in Men (FORMEN) study.
- 参照URL
- https://researchmap.jp/imai_n/published_papers/42300217
- 著者
- 著者（英）
- Katsuyasu Kouda,Yuki Fujita,Chikako Nakama,Kumiko Ohara,Takahiro Tachiki,Junko Tamaki,Akiko Yura,Jong-Seong Moon,Etsuko Kajita,Nami Imai,Kazuhiro Uenishi,Masayuki Iki
- 担当区分
- 概要
- 概要（英）
- BACKGROUND: Central obesity as measured by waist-to-hip circumference ratio (WHR) has been reported to be associated with renal hemodynamics and function. However, the adipose component of WHR, which is a composite measure of fat mass and fat-free mass, is small, particularly in nonobese subjects. Trunk-to-peripheral fat ratio as measured using dual-energy absorptiometry (DXA) is a more precise method for evaluating central fat distribution than WHR. The present study investigated the cross-sectional association between DXA-measured trunk-to-peripheral fat ratio and estimated glomerular filtration rate (eGFR) in community-dwelling elderly Japanese men. METHODS: Participants were 575 men aged ≥65 years at the time of the baseline survey of the second Fujiwara-kyo Osteoporosis Risk in Men (FORMEN) cohort study. Trunk-to-appendicular fat ratio (TAR) was calculated as trunk fat divided by appendicular fat (sum of arm and leg fat), and trunk-to-leg fat ratio (TLR) as trunk fat divided by leg fat. RESULTS: eGFR values significantly decreased from the lowest to the highest quintile of TAR/TLR. After adjusting for potential confounding factors including whole-body fat, the highest quintile of both TAR and TLR showed statistically significant odds ratios for the risk of eGFR <60 ml/min/1.73 m2, relative to the lowest quintile. In addition, a significant decreasing trend was observed for eGFR values from the lowest to the highest quintile of TAR/TLR after adjusting for confounding factors including whole-body fat. CONCLUSION: Elderly men with a large trunk-to-peripheral fat ratio tended to have a lower eGFR. This association occurred independently of that between whole-body fat and eGFR.
- 出版者・発行元
- 出版者・発行元（英）
- 誌名
- 誌名（英）
- Environmental health and preventive medicine
- 巻
- 28
- 号
- 開始ページ
- 30
- 終了ページ
- 30
- 出版年月
- 2023年
- 査読の有無
- 査読有り
- 招待の有無
- 掲載種別
- 研究論文（学術雑誌）
- ISSN
- DOI URL
- https://doi.org/10.1265/ehpm.22-00279
- 共同研究・競争的資金等の研究課題