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最終更新日：2024/02/02
枝 伸彦
エダ ノブヒコ
(Nobuhiko Eda)
論文
- タイトル
- タイトル（英）
- Whole-body cryotherapy enhances the expression of heat shock protein 70 and related hormones
- 参照URL
- https://researchmap.jp/7000005037/published_papers/35888984
- 著者
- 著者（英）
- Nobuhiko Eda,Kazuhiro Shimizu,Ai Takemura,Emi Narumi,Mariko Nakamura,Masako Hoshikawa,Michiko Dohi
- 担当区分
- 筆頭著者
- 概要
- 概要（英）
- BACKGROUND: Whole-body cryotherapy (WBC) is used as a conditioning method for athletes. However, the scientific evidence for its effects is still insufficient. OBJECTIVE: To elucidate the effects of transient WBC on the expression of heat shock protein (HSP) 70 and the secretion of related hormones in humans. MATERIALS AND METHODS: The participants in this study were six healthy adult men. WBC was performed for 3 min in a booth at a temperature in the range of -150 to -120°C, and measurements were taken immediately before (Pre), immediately after (Post), and 60 min after WBC (Post60). For measurement of core body temperature (gastrointestinal temperature), participants ingested a capsule-type wireless temperature sensor. The body surface temperature was measured using a noncontact thermometer, and measurements were taken at four sites on the body surface (chest, abdomen, front of the thigh, and front of the lower thigh). Leukocyte count, lactate dehydrogenase, creatine kinase, hemoglobin, hematocrit, adrenaline, noradrenaline, cortisol, adrenocorticotropic hormone (ACTH), erythropoietin, and HSP70 in the collected blood were measured. RESULTS: The results showed a decrease in body surface temperature and an increase in noradrenaline and ACTH immediately after WBC. In addition, the core body temperature decreased 60 min after WBC, accompanied by an increase in HSP70 expression. CONCLUSION: WBC may increase HSP70 expression via noradrenaline and ACTH. The results of this study suggest the usefulness of WBC in triggering protein synthesis and the maintenance of immune function after training.
- 出版者・発行元
- 出版者・発行元（英）
- 誌名
- 誌名（英）
- CryoLetters
- 巻
- 43
- 号
- 2
- 開始ページ
- 83
- 終了ページ
- 90
- 出版年月
- 2022年3月
- 査読の有無
- 査読有り
- 招待の有無
- 掲載種別
- 研究論文（学術雑誌）
- ISSN
- DOI URL
- 共同研究・競争的資金等の研究課題